Right-handed pitcher Luis Medina was signed by the Yankees as an international free agent on July 8, 2015. Out of Nagua, Dominican Republic for $280,000.

2016

In his first professional season, Medina started three games for the Dominican Summer League Yankees where he did not record a decision and allowed just one run in 4 2/3 innings of work while striking out four and walking four.  He only allowed two hits before a minor injury caused him to be shut down for the remainder of the season.

2017

Medina opened the 2017 season with the DSL Yankees once again, this time he was 1-1 with a 5.74 ERA in four games, three starts while striking out 17 batters in 15 2/3 innings of work.

He was promoted to the Pulaski Yankees in August, where he pitched in an additional six games, all starts.  With Pulaski, he was 1-1 with a 5.09 ERA and 22 strikeouts in 23 innings of work.